26.12.2023
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Vitiligo Disease

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Medicine now has many tools for treating various diseases. However, science knows very little about such a rare pathology as Vitiligo disease. To understand what this phenomenon is, you need to understand the features of the manifestation of the disease and the causes of its occurrence. Visually, vitiligo looks like a violation of pigmentation, which is characterized by the formation of bleached spots on the skin. This property of the disease is called depigmentation – the disappearance of the pigment melanin from certain areas of the skin. Let’s see what vitiligo is and how to cure it.?

The causes of the disease

Science knows neither the exact causes, nor the mechanism of development of vitiligo. There is an assumption that the appearance of vitiligo disease can be explained by the following factors:

  • exposure to certain chemicals or drugs;
  • pathology of the autonomic nervous system;
  • endocrine organ diseases;
  • hereditary predisposition;
  • chronic diseases.

Some experts believe that factors provoking other autoimmune skin diseases contribute to the development of vitiligo: immune disorders, combined with injuries, inflammatory and necrotic lesions of the skin, intoxication, and the infectious process. The occurrence of vitiligo disease is also associated with parasitic infections, an imbalance in the minerals, vitamins, deficiency of iron, copper, selenium and zinc.

The main signs and symptoms

The main manifestation of the disease is white spots on the body. Foci of the disease can occur at any age, often in childhood and adolescence, can form in all areas of the skin. Those places where the skin is most injured are most at risk of the appearance of depigmented areas – spots occur on the legs, knees, hands, elbows.

In the foci of vitiligo, sweating is disturbed, the skin becomes unable to respond normally to cold and heat. The hair on the whitened parts of the body in many patients also bleaches. Individual spots can disappear spontaneously even without treatment, but with the progression of the disease, foci of depigmentation can form at the sites of recent injuries, friction or pressure on the skin.

The initial stage of vitiligo is very weakly expressed. It is characterized by minor foci of depigmentation – small spots that look like a noticeable, but not particularly eye-catching cosmetic defect that is easy to mask with clothing. Gradually, bright spots on the skin enlarge and combine, forming large areas of milky white color..

Vitiligo disease does not cause any disturbing symptoms, it is not contagious, but it is difficult to cure. Vitiligo is perceived by patients as a serious aesthetic defect, so the disease can cause severe psychological discomfort. After tanning, the colorless areas become very noticeable, the affected areas of the skin are very sensitive to ultraviolet and quickly “burn out”.

Diagnostic Methods

Experts diagnose vitiligo on the basis of the existing clinical picture, examining the characteristic foci of depigmentation – white spots on the arms, legs, trunk. When making a diagnosis, difficulties almost never arise, it is more difficult to reliably detect the causes of Vitiligo disease. If the dermatologist is not sure of the diagnosis and suspects other skin pathologies (lichen, psoriasis, neurodermatitis), the patient is referred for additional examinations.

Vitiligo treatment

A variety of factors contribute to the onset of the disease, so its treatment requires an integrated approach. However, dermatologists do not yet have a clear scheme and reliable methods for treating vitiligo and stain removal. Most therapeutic measures are aimed at preventing the progression of the disease and reducing depigmented lesions on the skin..

Diet food

Vitiligo disease develops under the influence of metabolic disorders, and therefore, a special diet is an important condition for its successful treatment and getting rid of spots. The patient needs to eat, observing the following rules:

  • adhere to a fractional diet;
  • start each main meal with fresh vegetables or fruits;
  • consume foods rich in copper, manganese, selenium – eggs, meat, sea fish, seafood, cottage cheese, nuts, rose hips, wheat bran, legumes, crops;
  • refrain from overly spicy dishes, alcohol, foods with preservatives, convenience foods;
  • do not eat fried, but eat food baked in the oven, steamed or boiled.

Local treatment

The following ointments, creams, gels and lotions are used as local preparations for the treatment of Vitiligo disease:

  • hormonal ointments that slow down the breakdown of melanin in skin cells;
  • medications that stimulate the production of melanin;
  • drugs based on calcineurin inhibitors;
  • cosmetic products masking white spots (Covermark, Vitadye cosmetics, products for tanning or whitening unaffected skin).

For hormonal treatment of vitiligo, potent corticosteroid drugs, such as Fluticasone and Flixotide, are used. They are used continuously for three months (once a day) or six months intermittently: for 15 days, the product is applied to vitiligo spots, followed by a 15-day break, and this is repeated six times for six months.

To stimulate the synthesis of melanocytes (skin pigment cells) in case of illness, a lotion of vitiligo stains “Melagenin” is prescribed. The solution is applied to depigmented areas of the skin once a day, using until the desired therapeutic effect is obtained. If necessary, take short breaks in treatment. Remedies for vitiligo based on calcineurin inhibitors (Elidel, Protopic) are used twice a day for six months.

Systemic therapy

Vitiligo disease requires an individual approach when prescribing systemic drugs. In the complex treatment of the disease, the following groups of medicines can be used:

  1. Photosensitizers. They increase sensitivity to solar radiation. An example of such drugs is Vitil. It is taken continuously for six months, children consume from 6 to 12 years – 1 tablet 2 times a day, adults – 1 tablet 3 or 4 times.
  2. Corticosteroids. 0 These are hormone-acting drugs that help stop the progression of vitiligo. For example, betamethasone or dexamethasone. These drugs take 5 mg per day, the dose of medication for the child is reduced by half. Assign funds for a period of 6 months to 2 years.
  3. Immunomodulators. These agents stimulate and support the immune system. With vitiligo, it is preferable to use natural remedies – phytopreparations. An example is Echinacea. Adults and children over 12 years of age should take 1 tablet 3-4 times a day. Continuous medication is allowed for a period of not more than 8 weeks.
  4. Vitamins, minerals, nutritional supplements. Vitiligo patients are prescribed ascorbic and pantothenic acid, vitamins B1 and B2, iron preparations, 1% copper sulfate solution. Laboratory blood tests can be done to determine how to treat a patient and determine the exact dosage of drugs to treat the disease..

Physiotherapy

Physiotherapy is very effective in treating vitiligo disease. The most effective types of physiotherapy are:

  • UVB-therapy – dosed ultraviolet irradiation of the affected skin with a special lamp;
  • PUVA therapy – irradiation of the skin with long-wave ultraviolet radiation in combination with photosensitizing drugs;
  • laser therapy – exposure to vitiligo-affected skin with laser radiation of various powers;
  • electrophoresis to lesions of 0.5% copper solution.

Folk remedies

After trying different methods of treating the disease and never finding how to get rid of white spots on the body, patients often use unconventional drugs. Traditional medicine includes many home recipes that are good for vitiligo. The most effective are the following:

  • Hypericum infusion. Pour 1 teaspoon of grass with 0.2 l of boiling water and insist for half an hour. The resulting solution should be taken after meals, 3 times daily. The course of treatment lasts 3 weeks. After it, it is recommended to take a week break, and then take a second course of taking the drug.
  • Hypericum ointment. Mix the finely chopped grass with olive oil in a proportion of 1:10. Boil in a water bath, let cool, then strain. Store the resulting ointment in a dark place. Compresses are made from it, which must be applied to the foci of vitiligo once a day for 30 minutes. The duration of treatment is 40 days..
  • Infusion of mountain arnica. 40 g of grass pour 0.4 l of boiling water, leave for 20 minutes. Take 100 ml four times a day before meals.
  • Compresses of red clay and ginger juice. Mix the components in equal parts. Distribute the resulting mixture on a piece of gauze, then apply to the affected vitiligo zones. Keep the compress on the skin until the product is completely dry. There are no treatment time limits.

Surgical intervention

There are several time-tested and innovative methods of surgical treatment of vitiligo, however, all of them have contraindications and do not guarantee the complete elimination of the disease. Skin operations require modern high-tech equipment, so the most effective of them require treatment in Moscow or in foreign clinics. Surgical intervention for vitiligo may be as follows:

  • Skin transplant. The operation is performed in the absence of disease progression. The lesions are removed, and healthy skin is implanted in their place, which is taken from other sites.
  • Transplantation of melanocytes. Melanocytes grown from the patient’s pigment cells are placed on a special carrier, which is then applied to depigmented skin areas..
  • Autologous mini-grafts. In the foci of vitiligo, skin microtransplants are planted. This method is more complicated than transplanting whole flaps of skin, but at the same time it has fewer risks and side effects..

How to treat vitiligo in children

Almost all methods prescribed by adults are used to treat a disease in a child. The exception is systemic therapy with hormonal drugs. It is used only in the presence of strict indications, for a minimum time and at the lowest therapeutic doses. Children under 12 years of age are contraindicated in sessions of UV irradiation of the skin and PUVA therapy.

According to the famous pediatrician, in the treatment of this disease it is important to take care of the psychological state of the child. If peers tease him, and ill-mannered people constantly consider spots on the skin, you need to try to find the child to communicate with other people suffering from vitiligo – this will help him overcome emotional problems.

Disease prevention

After a successful recovery from vitiligo, it is important to follow preventive measures that will prevent the disease from returning:

  • carefully protect the skin from injuries, burns, cuts, insect bites;
  • avoid wearing tight clothing, uncomfortable shoes, jewelry that can rub your neck or fingers;
  • refrain from a long stay in the cold or under the sun, do not sunbathe, do not visit the solarium;
  • eat right, monitor the balance of vitamins and valuable elements;
  • avoid contact with chemical compounds;
  • undergo regular medical examinations.

Photos before and after skin disease treatment

You can understand how the skin condition can improve as a result of vitiligo treatment by looking at the photos of people before and after treating the disease. Placed below are pictures of skin areas affected by vitiligo that will give you the opportunity to approximately evaluate the effectiveness of therapy and help determine the strategy for combating this poorly understood disease.

Reviews

Maria, 27 years old: For the first time I had such spots on my back, and then on the feet and hands, even when I was just a child. I was injected intramuscularly with vitamins B, given iron preparations. The disease stopped, and the second time began to progress a little about six months after pregnancy, but nothing happened. Now the spots on the skin began to grow again, while vitamins with selenium and copper sulfate were prescribed for 2 months of treatment. I’ll see if there will be improvements.

Elena, 19 years old: When white spots appeared on the skin, my mother immediately led me to the doctors. They were treated with injections, pills, then phototherapy. A few months later they said that there was no progress in vitiligo, and everything was fine. For prevention, some minerals and vitamins were also given in courses. Since then, nothing has appeared. I was told that maybe there will never be these spots on the skin again, because the disease was cured in time.

Eugenia, 23 years old: Vitiligo appeared after a course of injections of antibiotics. The dermatologist did not prescribe anything, he said that there was no treatment. I had to look for a normal doctor, went through a bunch of examinations and tests, finally prescribed treatment – vitamins, copper preparations and compresses for stains with Ammifurin. While there is no progress of the disease, but the spots on the skin remain, and I can’t reduce them in any way.

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